Sinequan is an Antidepressants.Depression is an all-pervasive sense of sadness and gloom. In some patients with depression, an imbalance in levels of neurotransmitters in the brain may be the cause of the depression. Neurotransmitters are chemicals that nerves use to communicate with each other. Neurotransmitters affected by sinequan include serotonin, norepinephrine, acetylcholine, and histamine. Sinequan(Doxepin) may elevate mood by raising the levels of serotonin and norepinephrine. It also blocks the activity of acetylcholine and histamine.
Synonyms: Doxepin, Doxepin HCL, Doxin.

How to Use Sinequan
The usual dose of Sinequan(doxepin) is 75 to 300 mg daily administered at bedtime or in three divided doses. Doses greater than 300 mg daily are not more effective. Optimal improvement in depressive symptoms is seen after 2-3 weeks; anti-anxiety effects occur much sooner.

Sinequan Side Effects
The most common side effect of doxepin is drowsiness. Drowsiness improves as therapy continues. Other side effects associated with doxepin include blurred vision, urinary retention (difficulty urinating), dry mouth, constipation, weight gain or loss, and low blood pressure when rising from a sitting position (orthostatic hypotension). Rash, hives, rapid heart rate, seizures, and hepatitis are rare side effects. Doxepin also can cause elevated pressure in the eyes of some patients with glaucoma.

Sinequan Interaction
Tricyclic antidepressants should not be used with monoamine oxidase inhibiting drugs, for example, tranylcypromine (Parnate), because high fever, convulsions, and even death may occur from such combinations.Cimetidine (Tagamet) increases the breakdown of doxepin by the liver and can increase doxepin blood levels, possibly causing side effects from doxepin.

Sinequan Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222.

Sinequan Notes
Do not share this medication with others. Laboratory and/or medical tests should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Sinequan Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. .

Sinequan Uses
Sinequan is an antidepressant used in the treatment of depression in adults. It works by restoring the balance of natural chemicals (neurotransmitters) in the brain, thereby improving mood and feelings of well-being.Sinequan should not be used in children or teenagers due to lack of proven effectiveness in treating depression in children. Also, there have been reports of hostility and thoughts of suicide or self-harm occurring in some children using the drug.

Sinequan Other Uses
To know more about other uses of the drug consult ur doctor.

Sinequan Storage
Doxepin should be stored below 30 C (86 F) in a tight, light resistant container.

Sinequan Precaution
Before taking Sinequan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., unstable heart disease, recent heart attack), high or low blood pressure, liver disease, other mental/mood disorders (e.g., bipolar disorder), seizures, severe kidney disease, stomach bleeding, thyroid problems, untreated mineral imbalance (e.g., hyponatremia). Breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.